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About Patient Zero
Patient Zero is a paid strategy game made with AI by @stuart30, and it plays right here in your browser.
You are the outbreak
Patient Zero flips the zombie apocalypse on its head: you don't survive it — you cause it. From a strategic top-down view you watch two sleepy villages, a bustling small town, and a dense city with a military base on its edge. Your only weapon is a syringe full of a very bad idea.
Start the chain reaction
Pick your strain, click a crowded street, and watch the first victim turn. Every zombie spreads the virus on contact — one bad decision by a local cop can cost a whole district. Police patrols respond fast, and if the outbreak fizzles out, you lose.
Evolve the horde
Every turn feeds your Mutation Lab. Spend Mutation Cores to make the horde faster, tougher, and meaner — or grow a hulking Brute that soaks bullets and smashes through the city's defense. Reach the infection quota before the military cleans up.
- Real-time strategy with a single, perfect weapon: the injection
- Four pressure zones: 4 villages, 2 town, 1 city + military base
- Police and military AI that hunts your horde
- Customise your run each time with different upgrades added to your vial
- Win by overrunning the region — lose if the outbreak is contained

